Educational Articles
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Serotonin is a neurotransmitter produced by the body that regulates mood, sleep, body temperature, pain perception, blood vessel constriction, gastrointestinal function, and even blood clotting. An animal with serotonin syndrome experiences excessive effects of serotonin. This handout reviews the causes, diagnosis and treatment.
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Shaker syndrome is a condition involving generalized head and body tremors in dogs. The condition is often seen in small-breed, white dogs, although dogs of any size and color may be affected. The cause is unknown but thought to be autoimmune due to its response to treatment with steroids.
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Shar-Pei recurrent fever syndrome is a hereditary condition that affects nearly one in four Shar-Pei dogs. Affected dogs experience recurrent episodes of fever and inflammation, with no identifiable underlying cause. Inflammatory cytokines released during fever episodes contribute to the production of a protein called amyloid which is then deposited in a variety of internal organs, resulting in a condition known as amyloidosis. Signs that may accompany the fever episodes include swelling of the hocks and muzzle, abdominal pain, vomiting, and diarrhea. Non-steroidal anti-inflammatory drugs are often prescribed to reduce fever and alleviate discomfort. Colchicine is the drug of choice for the long-term treatment. Affected dogs can often be managed, but the condition will affect them for the remainder of their lives. If your dog is already showing signs of chronic kidney disease, your veterinarian will also develop a treatment plan to address the kidney disease.
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Ferrets commonly develop skin diseases, including infections with parasites (fleas, mites, ticks), bacteria, viruses (distemper), and fungus (ringworm). They are also subject to both benign and malignant tumors, including mast cell tumors. Adrenal tumors also cause hair loss and itchy skin in ferrets. All skin problems should be brought to the attention of your veterinarian, who will recommend the most appropriate treatment for the specific problem.
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Solar dermatitis is a skin disease caused by exposure to the sun. It occurs mainly in cats with white or pale patches of skin that are non-pigmented areas. The most commonly affected areas in the cat are the ears, but the nose and the eyelids are sometimes involved. Your veterinarian will recommend taking a tissue biopsy from the affected area if there is any concern that the condition may be progressing to squamous cell carcinoma.
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Spondylosis deformans is a condition that affects the vertebral bones of the spine and is characterized by the presence of bony spurs or osteophytes along the edges of the bones of the spine. Spondylosis deformans is a chronic condition that is associated with aging and most cats show no symptoms. This condition is usually diagnosed from X-rays of the spine. Treatment recommendations depend on the individual cat and whether they are showing any clinical signs, such as pain and difficulty with movement.
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Spondylosis deformans is a condition that affects the vertebral bones of the spine and is characterized by the presence of bony spurs or osteophytes along the edges of the bones of the spine. Spondylosis deformans is a chronic condition that is associated with aging and most dogs are free of symptoms. This condition is usually diagnosed from radiographs of the spine. Treatment recommendations depend on the individual dog and whether they are showing any clinical signs such as pain and difficulty with movement.
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Squamous cell carcinoma (SCC) is a tumor of the cells that make up the contact or upper layer of the skin. UV light exposure has been described as a developmental factor in people and appears to be associated with its development in cats. Areas affected include the ear tips, skin, toes, or peri-ocular region. Fine needle aspiration or biopsy may be performed for diagnosis. The metastatic rate does not appear overly clear, though staging is always recommended. SCC of the toe can occur as a primary tumor or may have spread from the lung (lung-digit syndrome). Surgery is almost always recommended in any case of SCC; the role of chemotherapy is controversial. Radiation therapy has an excellent response rate in cats with the SCC affecting the nasal planum and may give long-term tumor control.
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Staph (or staphylococcal) dermatitis is an inflammatory skin condition that the skin caused by a group of bacteria called Staphylococcus. Any disorder that causes itching or a change in the skin’s environment can create the ideal conditions to allow Staphylococcus to become a problem. This handout discusses Staphylococcus dermatitis in dogs, as well as a hypersensitivity (allergic) reaction to this bacteria. The clinical signs of these conditions, along with diagnosis, treatment, and prognosis, are outlined.
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Strokes are rare in cats. Some causes include a blood clot such as a thrombus or embolus that lodges in a cerebral blood vessel, cerebral bleeding from trauma, or a blood clotting disorder; however, the cause is often unknown. Signs of a stroke are variable depending on the regions of the brain affected and the degree and duration of blood and oxygen deprivation. Magnetic resonance imaging is the ideal diagnostic test for diagnosing a stroke. Treatment is complex and there is no guarantee of complete success. Your veterinarian will help you assess progress and plan remedial action.
