Educational Articles

  • Spinosad (brand name Comfortis®) is an antiparasitic used to kill adult fleas and to prevent and treat flea infestations in dogs and cats. It may be used off label (extra label) to treat other parasites and in other animals. It comes in an oral tablet form.

  • Spironolactone is given by mouth and is used off label to treat congestive heart failure, fluid accumulation, and other cardiovascular problems. Common side effects include increased drinking and urinating, mild decreases in energy, mild electrolyte imbalances, or vomiting/diarrhea. Do not use in pets that are allergic to it, have elevated potassium levels, Addison’s disease, acute kidney failure, significant kidney disease, that are not urinating or that may be used for breeding. If a negative reaction occurs, please call your veterinary office.

  • Spironolactone + benazepril (brand name Cardalis®) is a combination aldosterone antagonist (spironolactone) and angiotensin-converting enzyme inhibitor or ACE inhibitor (benazepril) used to treat certain types of congestive heart failure in dogs. Use to treat other heart conditions or in other species is "off label" or "extra label". Spironolactone + benazepril comes in chewable meat-flavored tablet form.

  • Spironolactone + hydrochlorothiazide is a combination aldosterone antagonist (spironolactone) and thiazide diuretic (hydrochlorothiazide) used to remove excess fluid and salt from the body in cats and dogs. This medication can be used in combination with other drugs to lower blood pressure and for protective effects on the heart muscle. It has also been used in dogs with fluid-up in the abdomen due to liver failure.

  • Spondylosis deformans is a condition that affects the vertebral bones of the spine and is characterized by the presence of bony spurs or osteophytes along the edges of the bones of the spine. Spondylosis deformans is a chronic condition that is associated with aging and most dogs are free of symptoms. This condition is usually diagnosed from radiographs of the spine. Treatment recommendations depend on the individual dog and whether they are showing any clinical signs such as pain and difficulty with movement.

  • Squamous cell carcinoma is a tumor of the cells that make up the contact or upper layer of the skin. UV light exposure has been described as a developmental factor in people, though it is still in question as to the role for dogs. Several breeds are known to be predisposed to this type of cancer. About 30% of dogs with the digital form of the disease will have evidence of spread. Regardless of the location, surgery is typically the treatment of choice, and staging is usually recommended prior to any surgery.

  • St. John’s wort is given by mouth and is used over the counter to treat pain, depression, anxiety, and other conditions. Give as directed by your veterinarian. The most common side effects include gastrointestinal upset, sun sensitivity, skin reactions, allergic reactions, dry mouth, or restlessness. Do not use in pets that are allergic to it, pregnant, nursing, very young, or very old or debilitated. If a negative reaction occurs, please call your veterinary office.

  • Stanozolol is given by mouth and is used off label to treat poor appetite, anemia, tracheal collapse, and other conditions. Give as directed by your veterinarian. Side effects may include behavior changes, limb swelling, or prevention of heat cycles. Do not use in pets that are allergic to it, are pregnant, breeding, or nursing. Pregnant women should NOT handle this medication. If a negative reaction occurs, please call your veterinary office.

  • Staph (or staphylococcal) dermatitis is an inflammatory skin condition that the skin caused by a group of bacteria called Staphylococcus. Any disorder that causes itching or a change in the skin’s environment can create the ideal conditions to allow Staphylococcus to become a problem. This handout discusses Staphylococcus dermatitis in dogs, as well as a hypersensitivity (allergic) reaction to this bacteria. The clinical signs of these conditions, along with diagnosis, treatment, and prognosis, are outlined.

  • Stem cells are unspecialized cells that are capable of renewing themselves though cell division. Under certain conditions, they can become a specific tissue or organ cell. Stem cell therapy commonly refers to the process of placing stem cells from the body into diseased or damaged tissues, such as a torn ligament in the knee or perhaps an arthritic joint. This process is often referred to as regenerative medicine. Adult stem cells are capable of repair and regeneration of various tissues because they have the potential to differentiate into specialized cells of an organ. The most common use of stem cell therapies has been in the treatment of osteoarthritis in dogs and cats. Currently, there are no current guidelines with respect to stem cell therapy. Stem therapy should only be performed by a veterinarian with special training, who understands the benefits and limits of this therapy. It is important to have realistic expectations as positive outcomes cannot be guaranteed.

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