Educational Articles
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Collie Eye Anomaly (CEA) is a genetic mutation affecting many breeds that causes developmental defects in the eye that can lead to vision deficits or blindness. This defect can be diagnosed by a veterinary ophthalmologist between 6 and 8 weeks of age by visualizing spots of choroidal hypoplasia or a colobomas . It can be associated with microphthalmia or enophthalmia. It can lead to retinal detachment and blindness. Although laser repair of partial retinal detachments can be attempted if detected in early stages, there is generally no treatment for CEA. Vision varies depending on the extent of the lesions and some dogs will become blind. Prevention requires not breeding animals that carry the mutation and this can be achieved through genetic testing of breeding dogs.
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Color dilution alopecia is an autosomal recessive genetic disorder that affects dogs with dilute-colored coats causing hair loss. Some dogs will also be affected by secondary bacterial infections so topical management and pruritus treatments may be needed to improve the dog's comfort. Affected dogs and their relatives should not be bred.
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The complete blood count (CBC) assesses different parameters of the cells in the blood including total number, appearance, size, and shape. Red blood cells, white blood cells, and platelets comprise the cellular component of the blood.
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Constipation is infrequent or difficult passage of stool or feces and is typically a temporary condition. Though there are many causes of constipation in dogs, most cases are caused by ingestion of irritating or indigestible substances. Constipation is usually diagnosed through a physical examination and medical history. A rectal exam to rule out rectal strictures, tumors, foreign bodies, or other abnormalities may be done. Abdominal radiographs, blood tests, and urinalysis are valuable for a full diagnosis and development of a treatment plan. Biopsies may also be recommended if a rectal mass or stricture is suspected. Most cases of constipation are relatively easy to treat through the use of manual removal, enemas, and medications. The prognosis for constipation is determined by the exact cause.
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A Coombs’ test is used to test for a disease called autoimmune hemolytic anemia (IMHA). IMHA is a condition where the immune system breaks down or destroys red blood cells, leading to anemia. The test detects the presence of immunoglobulins (antibodies) on the surface of red blood cells. Taken together, the physical findings and the laboratory data (such as a Coombs’ test) may suggest that immune-mediated destruction of red blood cells is the most likely cause of your pet's anemia.
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Corneal dystrophy is a term used to describe several conditions that occur in dogs and cause the corneas to become opaque. There are three major categories of corneal dystrophy: epithelial, stromal, and endothelial. Each is named by the anatomic location of the abnormal tissue and opacity.
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The cornea is the transparent, shiny membrane that makes up the front of the eyeball. With a corneal ulcer, fluid is absorbed from the tears into the stroma, giving a cloudy appearance to the eye. The most common cause of a corneal ulcer is trauma. Less common causes of corneal ulcers include bacterial infections, viral infections, and other diseases.
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This handout discusses the use of cryosurgery in pets. This technique involves the use of extreme cold to destroy abnormal or diseased tissues. A short discussion in included as to how the technique is used, and in what circumstances it may be appropriate to use.
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Treatment for Cushing’s disease using mitotane involves two phases: initiating phase and maintenance phase. Monitoring your dog’s food and water intake is very important. This handout provides detailed treatment instructions for dogs prescribed mitotane. Follow your veterinarian’s instructions carefully and report changes in your dog’s behavior to your veterinarian.
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Cutaneous histiocytosis is an uncommon condition in dogs. It is a non-cancerous increase in the number of reactive cells (histiocytes) caused by an immune system dysfunction. It generally manifests as multiple bumps and nodules confined to the dog's skin. The clinical signs, diagnosis, and treatment of this condition are explained in this handout.
