Educational Articles
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Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The most common functional pituitary macroadenoma in the dog secretes the hormone ACTH, causing increased cortisol levels and Cushing’s disease. Non-functional macroadenomas cause clinical signs through compression of nearby structures resulting in vision changes, diabetes insipidus, and neurologic disorders. This handout explains the effects of these tumors on dogs, how they are diagnosed, and the treatment options available.
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Clinical signs of pituitary tumors depend on whether the tumor is functional or non-functional. Functional tumors can cause Cushing's disease in dogs and can cause acromegaly and insulin-resistant diabetes in cats. Non-functional pituitary tumors can enlarge to cause neurological signs. Diagnosis is based on the history, bloodwork, urinalysis, and sometimes a CT scan or MRI. Medical therapy is often the treatment of choice for functional tumors. Radiation therapy is another option and is usually the primary treatment for non-functional tumors.
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Plaque forms on teeth shortly after eating and within 24 hours begins to harden, eventually turning into tartar. Tartar serves as a place for bacteria to grow, leading to gingivitis. As gingivitis worsens, periodontal disease develops, which includes inflammation, pain, and tooth loss. Prevention of plaque and tartar build-up is key. Use VOHC-accepted food and/or water additives, wipe or brush your dog's teeth daily, and have your veterinarian perform regular dental cleanings.
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Plasma cell tumors develop as a result of dysregulated production of plasma cells and are relatively uncommon in dogs and cats. Some plasma cell tumors are benign and the most common locations for these tumors are the head, feet, lips, mouth, and ears. The treatment of choice for benign plasma cell tumors is surgical removal, with little to no recurrence if completely excised. Conversely, multiple myeloma is a very malignant cancer that is usually treated with chemotherapy.
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Platelet-rich plasma or PRP is a form of regenerative medicine where the platelet and protein components of blood are retrieved from a patient and then injected back into the patient at the site of inflammation. PRP contains growth factors that appear to promote tissue regeneration and reduce inflammation. The procedure is not yet widely available and should only be performed by a veterinarian with specialized equipment and special training in this area.
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Mouthing, nipping, and biting are used by all puppies during social play with their littermates. Once they leave their littermates, you can easily teach them a new set of games that are appropriate for social play with people. It is important to provide puppies with outlets for appropriate play from the start. Puppies should never be punished for playing with their teeth, as it can cause them to become permanently fearful of people.
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Pleural effusion refers to the abnormal accumulation of fluid within the chest cavity. The fluid is not found within the lungs, but instead within the pleural sac, essentially meaning the lungs are floating in a chest that is full of fluid. There are several causes, including chylothorax, heart failure, and lung or chest tumors. Dogs presenting for pleural effusion are often experiencing shortness of breath and decreased oxygen intake; placing them into an oxygen cage provides some degree of immediate relief. Removing the fluid that surrounds the lungs will allow the dog to breathe more readily and this fluid can then be tested to identify the cause of the pleural effusion. The treatment and prognosis vary depending on the underlying cause.
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Pneumothorax is an accumulation of air outside the lungs, but inside the chest wall. The air outside the lung prevents the lungs from inflating normally, and can lead to lung collapse. There are several variations of pneumothorax.
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Pododermatitis is a term used to describe inflammation of the feet or paws. It can be caused by many disorders including infections, allergies, hormonal disorders, immune-mediated diseases, tumors or cancers. Diagnostic testing is discussed. Effective treatment must be directed toward the underlying cause.
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Polycystic kidney disease (PKD) is an inherited kidney disease that is common in cats, but uncommon in dogs. Dogs with polycystic kidney disease develop multiple fluid-filled cysts within the kidney, with the number and size of these cysts increasing with age. As the kidney cysts displace larger amounts of functioning kidney tissue, the dog begins to show signs of chronic kidney disease. There is no specific treatment for polycystic kidney disease; treatment is centered on alleviating the signs of chronic kidney disease.
