Illustrated Articles
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Meningoencephalitis is a term referring to inflammation of the brain and the surrounding fluid and tissues. Meningoencephalitis of unknown origin is a term used to describe those cases of meningoencephalitis in which MRI and cerebrospinal fluid analysis indicate the disease but diagnosis through histopathological analysis is not possible. Treatment typically involves immunosuppressant drugs, sometimes with the addition of antibiotics. The prognosis depends on several factors, which are also explained in this handout.
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Methylsulfonylmethane is given by mouth and is used over the counter and off label to treat inflammatory conditions such as arthritis. Give as directed by your veterinarian. Side effects are uncommon but may include stomach upset, restlessness, or tiredness. Do not use in pets that are allergic to it or that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.
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Miconazole topical is an antifungal used in the treatment of skin infections caused by yeast in cats and dogs. It may be used “off-label” or “extra label” for other conditions and in other animals. It may be specially compounded and/or combined into a formulation with other medications. Miconazole topical comes in a variety of forms.
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Mitral valve disease is often one of the earliest indicators of heart disease that could lead to heart failure. It is more common in small dogs than large breeds. The earliest sign of a leaking mitral valve is normally a heart murmur, and eventually, congestive heart failure develops. Diagnostic tests will help determine what stage your dog is at and can help guide treatment. Treatment varies depending on the results of the various tests. Many patients can live a good quality of life for many years after diagnosis.
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Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.
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Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury, or strain, caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in dogs and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.
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This handout discusses muscular dystrophy (MD), primarily in dogs. The cause of the disease is a defect in the proteins found in muscle cells. It is often an inherited disease, usually affecting young dogs. Clinical signs (usually starting as muscle weakness) and diagnosis of the condition are outlined. There is no effective treatment for the condition.
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Myasthenia gravis is a disease in which there is a malfunction in the transmission of signals between the nerves and muscles. Dogs with myasthenia gravis exhibit extreme weakness and excessive fatigue. There are two forms: inherited and acquired. Anti-acetylcholinesterase medication and immunosuppressive therapy will likely be required for the life of the dog.
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A narcoleptic episode involves sudden collapse and loss of movement in which the pet literally falls asleep, often while physically active, then wakes up abruptly and proceeds as if nothing happened. Although you may not be able to stop the episodes, you may be able to reduce the frequency and severity of events by identifying possible patterns that precipitate the incidents.
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Nose Bleeds (Epistaxis) in dogs can be extremely unsettling for the pet owner. Most acute (sudden) nosebleeds are caused by simple trauma or by upper respiratory tract infections. This handout discusses nosebleeds in dogs, the various causes of this condition, first aid recommendations and possible testing to find the root cause of the problem.